- Product Description
Premium Andrographolide Powder Supplier | 98% HPLC Purity
Shaanxi Bolin Biotechnology sells pharmaceutical-grade Andrographolide Powder that is up to 98% pure as confirmed by HPLC. It is made from the best parts of the Andrographis paniculata plant's upper parts. Our ISO-certified factory has been making more than 3000 kg of goods every month since 2012, providing steady quality to global B2B partners.
Our advanced extraction technology isolates this labdane diterpenoid with precise molecular integrity (C₂₀H₃₀O₅, CAS 5508-58-7). The powder is white, solid, and meets CP/USP standards. Its freezing point is between 228°C and 232°C, and its optical rotation range is between -124° and -127°.
We solve important problems in the industry, like inconsistent batches, low absorption of crude extracts, and bitter formulations. Our 25,800-acre approved growing base makes sure that raw materials can be tracked, and six stages of quality testing make sure that they meet EU standards for heavy metals and pesticides.
What Makes Our Andrographolide Powder Different?
Pharmaceutical-Grade Purity
Your formulas need to be trusted. Our Andrographolide Powder is ≥98% pure because we use a special process to get rid of impurities like Dehydroandrographolide and Neoandrographolide. For your anti-inflammatory and immunomodulatory uses, this high dosage gives you accurate dose.
The HPLC analysis of every batch is done in our cutting-edge lab. You get reliable active ingredient profiles that help make sure that URTI treatments, viral fever management, and liver support formulas work the same way every time.
Source-to-Science Traceability
From the ground up to the shipment, we handle quality. Our registered growing base grows more than 800 plant types on approved land, making sure that the stems and leaves we gather have the right amount of andrographolide.
Verification of raw materials starts at harvest time. Based on the amount of active compounds, our botanists choose the best Andrographis paniculata. This vertical merger gets rid of the differences between suppliers that hurt the performance of your product.
Superior Thermal Stability
Unlike liquid extracts, which lose their effectiveness over time, our solid powder stays effective when stored normally. Because it is lipophilic and stable in acidic environments, it is perfect for making products that don't go through the stomach.
Our thermally safe API gives your R&D teams more options for how to make new products. Our powder can handle high temperatures during processing without losing its biological effectiveness, so you can use it to make pills, capsules, or functional drinks.
Technical Specifications
| Parameter | Specification |
|---|---|
| Active Ingredient | Andrographolide |
| CAS Number | 5508-58-7 |
| Molecular Formula | C₂₀H₃₀O₅ |
| Molecular Weight | 350.45 g/mol |
| Purity Levels | 5%, 10%, 50%, 98% (HPLC) |
| Appearance | White to off-white crystalline powder |
| Melting Point | 228-232°C |
| Optical Rotation | -124° to -127° (anhydrous ethanol) |
| Solubility | Lipophilic, low water solubility |
| Source Material | Andrographis paniculata stem & leaf |
| Test Method | HPLC/UPLC |
| Standards Compliance | CP, USP, EP |
| Production Capacity | 3000 kg/month |
| Storage Conditions | Cool, dry place; sealed container |
Applications Across Industries
Pharmaceutical Formulations
Our API-grade clarity helps your drug creation. The way that andrographolide blocks NF-κB supports treatments that have been shown to work for upper respiratory illnesses and inflammatory diseases. Pharmacokinetic simulation is possible with exact molecule weight and optical rotation factors.
Formulation scientists like that the powder can be mixed with solid tablet form excipients. The solid structure makes it easier to mix evenly, and the low impurity profiles lower the risk of bad reactions.
Nutraceutical Products
Health supplement companies use our standardized ingredients to make products that help the immune system. Our 50–98% pure range lets you find the best mix between price and effectiveness for your target markets.
With our high-purity processing, the bitter barrier problem goes away. If you start with clean, concentrated actives instead of raw plant material, your methods for sealing or covering will work better.
Functional Food Ingredients
People who are making new drinks and foods use our powder in health goods. Bioactivity is kept in hot-fill products and baked goods thanks to better stability during heat processing.
Our expert team gives advice on how to improve stability. We help you reach your dose goals in the easy-to-use forms that your customers like, like energy bars and fizzy pills.
Quality Assurance You Can Verify
Six-Step Testing Protocol
We don't just say we're good; we show it. Before it gets to your building, each production batch goes through strict checkpoints:
Screening of raw materials: confirming the name of plants using microscope and chemical fingerprinting
Testing for heavy metals (Pb, As, Cd, and Hg) according to the standards set by the EU Pharmacopoeia
Microbial Safety: Total plate count, yeast/mold, and disease screening according to HACCP rules
Quantification of active ingredient using HPLC and USP standards
Purity Verification: related drug research to find breakdown products
Third-Party Validation: Shipments come with independent lab certificates (SGS).
Certified Manufacturing Excellence
Our next-generation plant, which opened in 2024, is fully automated and uses closed-loop green technology. Our ISO 22000 and cGMP certificates show that we are dedicated to meeting the standards for pharmaceutical production.
With every sale, you get paperwork that is ready for an audit. Our batch records include full tracking from field positions to final packing, which helps you with regulation applications all over the world.
International Compliance
For global growth to happen, regional safety experts are needed. We keep our certificates up to date for KOSHER, HALAL, and a number of pharmacopoeia standards. When you use our appropriate ingredients in your products, they will be easier for regulators to approve.
Custom Solutions for Your Specific Needs
OEM Partnership Services
With our full OEM help, you can make your brand's idea come true. We come up with the formulas, make test batches, and make enough of your unique mixes to meet your needs.
Flexible Requirements: Need 30% andrographolide with certain additives? For your specific use, our R&D team tweaks rates to work best. Before business runs, ideas are tested in small batches (at least 50 kg).
Packaging Flexibility: We can make packaging that fits your supply chain, from 1 kg foil bags to 25 kg fiber drums. When you use private labeling services, your brand and safety paperwork are included.
Speed to Market: Our more than 80 professionals work together across areas to shorten the time it takes to create new products. From the first question to the first shipment, you have specialized project management.
Enhanced Bioavailability R&D
Our lab takes on the problem of absorption head-on. We improve oral absorption beyond what powder alone can do by using liposomal encapsulation, cyclodextrin complexation, and nano-emulsion technologies.
Work with our biological experts to create your own transport methods. To get the best treatment window for your product, we test its breakdown and absorption.
Why Global Partners Choose Bolin Biotechnology
Decade of Plant Extract Expertise
Since 2012, we've improved the ways we collect more than 800 plant types. Because of this knowledge, the process is more efficient than with common providers. Our creation of Andrographolide Powder is the result of years of work to improve yield, clarity, and cost-effectiveness.
Production is backed up by two high-tech facilities: a foundation plant built in 2015 and an automatic growth planned for 2024. With 3000 kg of monthly capacity that grows with your business, your supply chain can handle problems at a single spot.
Scientific Team You Can Consult
Over 80 specialists bring multidisciplinary perspectives to your challenges. Botanists advise on seasonal sourcing variations. Biochemical engineers troubleshoot formulation incompatibilities. Quality assurance experts interpret regional regulatory nuances.
This isn't transactional supplier relationship—it's technical partnership. We share analytical methods, provide stability study data, and co-author product monographs that strengthen your dossiers.
Sustainability Built Into Operations
Responsible sourcing meets business continuity. Our registered 25,800-acre planting base practices crop rotation and organic cultivation methods, ensuring long-term raw material availability without ecological degradation.
The 2024 facility's closed-loop water recycling and solvent recovery systems reduce environmental impact while lowering production costs. You gain competitive pricing from operational efficiencies, not compromised quality.
Frequently Asked Questions
Q: What's the difference between 5% and 98% purity grades?
A: Lower concentrations (5-10%) suit cost-sensitive nutraceuticals where higher dosing is acceptable. The 98% pharmaceutical grade provides maximum potency for clinical applications requiring precise milligram dosing. We recommend 50% as the optimal balance for premium dietary supplements.
Q: How do you address andrographolide's bitter taste in formulations?
A: High-purity powder actually reduces bitterness per dose compared to crude extracts containing multiple bitter compounds. We offer microencapsulation services and suggest enteric coating for tablets. Our technical team provides taste-masking protocols tested in various matrices.
Q: Can you provide samples for formulation trials?
A: Yes, we supply 50-100g samples with full analytical certificates. This allows your R&D team to conduct compatibility, stability, and dissolution testing before committing to commercial quantities. Sample requests typically ship within 5 business days.
Q: What documentation supports regulatory approval processes?
A: Each shipment includes Certificate of Analysis, MSDS, non-GMO declaration, allergen statement, and microbial test results. We provide Drug Master Files (DMF) support for pharmaceutical applications and maintain audit-ready batch production records spanning three years.
Q: How stable is andrographolide during product shelf life?
A: Our powder demonstrates <2% degradation over 24 months when stored properly (sealed, cool, dry conditions). We conduct accelerated stability studies per ICH guidelines and share protocols for finished product testing. Antioxidant synergies with vitamins C/E further enhance stability in multi-ingredient formulas.
Q: What's your minimum order quantity and lead time?
A: Standard MOQ is 25kg for stock specifications (98% purity). Custom purities may require 100kg minimum. Production lead time averages 15-20 days after order confirmation, with shipping method determining final delivery schedule. We maintain safety stock of popular grades for expedited orders.
Partner With a Certified Leader in Botanical Extracts
Ready to elevate your product formulations with pharmaceutical-grade Andrographolide Powder?
Contact our sales specialists today: sales1@bovlin.com














