Nicotinamide Powder

Premium Nicotinamide Powder – 99% Pure Vitamin B3 from Bolin Biotechnology

Shaanxi Bolin Biotechnology provides 99% purity pharmaceutical grade Nicotinamide Powder with rigorous USP and EP requirements for cosmetic, nutraceutical and pharmaceutical applications. It has been 8 years since we started delivering consistent high bioavailability Vitamin B3 powder to over 2,000 worldwide customers with our ISO certified facilities...

Our company advantage is our vertical integration, from our 25,800 acre certified planting base to innovative closed-loop extraction technologies commissioned in 2024. Each batch is confirmed for quality via six levels including HPLC assay analysis, heavy metal testing to less than 20ppm and microbiological safety examination. Our product is packaged with moisture management and guaranteed stable for 24 months. It overcomes 3 important issues in the industry: 1. Excellent solubility ( 1g/1mL water), 2. No niacin flush irritation, 3. Superior efficiency of NAD+ precursor for cellular energy metabolism.

What Makes Our Nicotinamide Powder Different?

Clean Vitamin B3 supplementation without the painful skin flushing of typical niacin with our flush-free solution. The powder was shown to be stable in the pH range of 6.0–7.5 thereby providing stability for formulations in the form of creams, capsules and liquid mixes.

It has superb flowability that your production teams will like. This is important in high speed encapsulation and tablet compression. Our crystal structure inhibits caking in automatic dosing systems, lowering down time and waste.

We manage every step from the soil to the transportation. Our botanists grow raw materials in contamination free zones. Our biochemical experts then use precise extraction to retain molecular activity while removing contaminants.

Technical Specifications

Key Properties That Drive Performance

Nicotinamide Powder is appreciated for its excellent physicochemical properties. It is a water-soluble amide derivative of Vitamin B3, easily absorbed in the gastrointestinal system without the vasodilation common with nicotinic acid.

The powder is hygroscopic and should be handled carefully. It is packed in fiber drums in moisture-barrier aluminum foil bags. This eliminates clumping due to humidity, which would impact dosage precision.

It melts in the temperature range 128-131°C allowing for heat sensitive processes. It may be included into thermoplastic extrusion for prolonged release matrices without degradation. Its bland taste characteristic also lends itself to flavoring in the form of chewable pills and gummies.

This powder has excellent stability on storage. Under optimal circumstances deterioration is less than 1% over a two year period. The increased shelf life decreases inventory risk, allows for transportation across long distances to foreign markets.

Proven Applications Across Industries

In Cosmetic Formulations

Our product is used by leading skincare companies at 2-5% concentrations to provide obvious anti-aging benefits. It prevents melanosomes from being transferred to lighten skin tone and stimulates the production of ceramides for better barrier function.

Fully compatible and may be used by your R&D teams in combination with peptides and retinol. pH is within a stable range to avoid hydrolysis in complicated emulsion systems. For the most stable serums, see our micro-encapsulated version that is oxidation resistant.

In the Nutraceutical Manufacturing

The supplement makers like the high bulk density, since it makes it easier to fill their capsules. You can get 500mg doses into #0 size capsules without a lot of excipients. This preserves the label claims while reducing the cost per unit.

It is a direct NAD+ precursor , which supports more than 400 enzymatic processes in the cellular energy metabolism. It is more bioavailable than ester derivatives, which is beneficial in formulations targeting healthy aging, cognitive function and metabolic wellness.

In the Pharmaceutical Industry

We have pharmaceutical grade material that complies with severe monograph standards for medicinal uses. It is used for Pellagra and to assist neuroprotective treatments in clinics.

Uniform particle size distribution of the powder helps to have uniform content in tablets. Its high compressibility decreases the requirement for binders, leading to simpler formulations and better dissolving rates.

In Animal Nutrition 

Our product is used by feed producers to avoid deficiency disorders in poultry and pigs. It improves the Feed Conversion Ratio (FCR) and enhances skeletal growth.

The anti-caking properties in premixes make the powder appropriate for use in automated blending systems. This guarantees correct dosage in large-scale manufacturing runs without segregation problems.

Quality Control You Can Trust

Every batch begins with validated raw materials from our approved growing base. We test for 238 pesticide residues using procedures compatible with EU. ICP-MS examination for heavy metals assures us the levels are well below legal limits.

Our 6-step quality methodology includes:

• Botanical identification of raw material
• HPLC monitoring of purity during procedure
• Testing for microbial contamination (total plate count, yeast, mold, pathogens)
• Active ingredient quantitation ±2% tolerance
• Third party verification by SGS or similar
• Stability testing at accelerated conditions

Each shipment is accompanied with a Certificate of Analysis. It comprises spectroscopic data, chromatograms and batch traceability codes. This material is used for your customer audits and regulatory filings.

Custom Solutions for Your Business Needs

We understand that one size does not fit all. Our OEM services are tailored to your needs:

Flexible Packaging Options: R&D experiments in 1kg aluminium bags to production scale in 25kg fibre drums. We can provide private labeling with your own brand name .

Custom Particle Sizes: Need super fine Nicotinamide Powder for topical applications? Or in a granular form for easier flow in mixing equipment? Our milling capabilities include 40 to 200 mesh ranges.

Formulation Support: Technical support for stability testing, dose optimization and compatibility studies. We assist you solve formulation problems before you go into full production.

Regulatory Documentation: For easier navigation through your compliance procedure, we provide DMF (Drug Master File) assistance, allergy statements, BSE/TSE certifications and non-GMO declarations.

Frequently Asked Questions

Q: How does your product prevent niacin flush?

A: Unlike nicotinic acid, the amide structure doesn't trigger prostaglandin-mediated vasodilation. This makes it suitable for sensitive skin applications and high-dose supplementation without discomfort.

Q: What's the recommended storage to maintain 99% purity?

A: Store in sealed containers below 20°C in low-humidity environments. Avoid direct sunlight and heat sources. Properly stored material retains potency for 24 months with less than 1% degradation.

Q: Can I use this powder in liquid formulations?

A: Yes, it dissolves readily at 1g per 1mL water. For long-term stability in aqueous solutions, maintain pH between 6.0-7.5 and add appropriate preservatives. Consider encapsulation for alkaline environments.

Q: How do you ensure consistent quality between batches?

A: We source raw materials from our controlled planting base and use standardized extraction protocols. Each batch undergoes HPLC fingerprinting to match reference standards. Batch-to-batch variation stays within ±2% for active content.

Q: Do you provide samples for testing?

A: Absolutely. We offer free samples (typically 50-100g) to qualified businesses. This allows you to validate performance in your specific application before committing to larger orders.

Q: What's your minimum order quantity?

A: For stock specifications, our MOQ is 1kg. For custom formulations or particle sizes, we typically require 25kg minimum. Contact Us to discuss your specific volume needs.

Partner with a Trusted Manufacturer

Ready to source pharmaceutical-grade Nicotinamide Powder that meets your exact specifications?

Contact our team at sales1@bovlin.com