- Product Description
Premium Sialic Acid Powder Supplier | 98% HPLC Grade Available

At Shaanxi Bolin Biotechnology, we provide Sialic Acid Powder with purities ranging from 1% to 98% (HPLC tested). Our high-quality N-Acetylneuraminic Acid (CAS: 131-48-6) is a fine white powder with high water solubility and heat stability up to pasteurization temperature.
Since 2012, we have state-of-the-art microbial fermentation technology in ISO 22000-certified facilities. We cultivate on 25,800 acres of plantations, using the latest biotech innovations and strict quality control. You are assured of consistent, high-bioavailability material ideal for baby formula, nutraceuticals and cosmeceutical applications, since each batch passes six-step testing including heavy metal screening to EU requirements.
Our product has a molecular weight of 309.27 g/mol and optical rotation of -30° to -33°. It is certified HALAL, KOSHER and HACCP for worldwide export.
| Parameter | Specification |
|---|---|
| Other Names | N-Acetylneuraminic Acid, NANA |
| CAS Number | 131-48-6 |
| Molecular Formula | C11H19NO9 |
| Molecular Weight | 309.27 g/mol |
| Purity Range | 1% - 98% |
| Test Method | HPLC |
| Appearance | White to off-white crystalline powder |
| Solubility | Excellent water solubility |
| Optical Rotation | -30° to -33° |
| Shelf Life | 24 months |
| Storage Conditions | Cool, dry place away from light |
| MOQ | 1 KG |
| Sample Availability | Yes |
COA
|
Item |
specification |
Result |
Method |
|
Sialic acid |
≥98.0% |
98.4% |
HPLC |
|
Physicochemical Control |
|||
|
Appearance |
Powder |
Complies |
Sense |
|
Color |
White |
Complies |
Sense |
|
Loss on Drying |
≤2.0% |
0.55% |
GB5009.3 |
|
Ash |
≤1.0% |
0.06% |
GB5009.4 |
|
PH |
1.8-2.3 |
2.04 |
CP2025 |
|
Heavy Metals |
|||
|
Pb |
≤0.5pm |
Complies |
GB5009.12 |
|
As |
≤0.4ppm |
Complies |
GB5009.11 |
|
Hg |
≤0.2ppm |
Complies |
GB5009.17 |
|
Cd |
≤0.5ppm |
Complies |
GB5009.15 |
|
Microbiological Control |
|||
|
Total Plate Count |
≤500cfu/g |
Complies |
GB4789.2 |
|
Mold & Yeast |
≤100 cfu/g |
Complies |
GB4789.15 |
|
E. Coli |
≤0.3 cfu/g |
Complies |
GB4789.38 |
|
Salmonella |
Negative |
Complies |
GB4789.4 |
|
staphylococcus aureus |
Negative |
Complies |
GB4789.10 |
|
Conclusion:Conform with Specification |
|||
What Makes Our Sialic Acid Powder Different?
Sustainable Microbial Fermentation
We make Sialic Acid Powder by high-efficiency microbial fermentation, not through the conventional method of animal extraction. This way you have a cost efficient, vegan friendly option that is consistently good quality from batch to batch.
You get predictable availability in your supply chain. Our method removes the seasonal changes that often happen with bird's nest collecting.
Superior Stability in Complex Formulations
Our substance retains its bioactivity when mixed with proteins, minerals, vitamins and other active elements. It is stable enough for inclusion in multi-component formulae without concern about deterioration during high temperature processing.
This temperature resilience makes it suitable for use in pasteurized goods and spray drying applications.
Traceable Quality from Soil to Package
All batches are sourced from our 25,800-acre approved planting bases recognized with the State Forestry Administration of China. Our team of over 80+ specialists guarantee quality via raw material verification, pesticide screening, microbiological safety testing and third-party verification.
Full paperwork to assist regulatory compliance in your target markets.
| Dimension | Bolin's Sialic Acid Powder | Other Companies |
| Purity | ≥98% (High Purity) | Lower Purity |
| Quality Control | Strictly Controlled Throughout Production | Inconsistent or Loose Standards |
| Preparation Method | Microbial Fermentation | Extraction Method |
| Raw Material Sources | Glucose, Peptone, Inorganic Salts, etc. | Natural Raw Materials |
| Production Yield | Higher Yield | Lower Yield |
| Production Cost | Lower Cost | Higher Cost |
| Safety | High Safety, No Chemical Residues | Potential Chemical Residues |
| Environmental Impact | Environmentally Friendly | Higher Environmental Impact |
Key Applications Across Industries
Infant Nutrition & Clinical Formulas
Your consumers in need of cognitive growth help will enjoy recipes fortified with our high purity substance. It is a natural component of human breast milk and is involved in synaptogenesis and brain ganglioside development.
Infant formula manufacturers utilize it in an attempt to make the nutritional profile of their product more similar to that of mother milk. It is added to goods for neurological health by clinical nutrition companies.
Immune-Boosting Nutraceuticals
Our component is a biological protection when you are designing supplements for immune system regulation. It blocks the attachment of pathogens to host cells, a process that is increasingly recognized in preventative health treatments.
It is a benefit to anti-aging formulas the function it plays in cellular communication. Your R&D team may exploit the terminal location on glycan chains to reinforce product effectiveness claims.
Premium Skincare & Cosmeceuticals
Leading skin care companies choose our substance for its ability to support cellular recognition and skin barrier restoration. Its stability in aqueous cosmetic bases is higher than standard bird’s nest extracts, providing your compositions a longer shelf life.
You may promote products with cleaner ingredient lists, yet still provide the bioactive advantages customers have come to expect from premium cosmeceuticals.

Our Complete Manufacturing Ecosystem

Two State-of-the-Art Facilities
We set up the base in 2015 with key extraction and purification technologies for early worldwide customers. With the new 2024 facility, the bar has been raised for efficiency and environmental responsibility, since it is 100% automated and utilizes closed loop sustainable technology.
Both plants combine precise automation and green processes with the strictest hygiene regulations.
Advanced R&D Laboratory Support
We help you with product development in three main areas. Optimised extraction processes improve bioavailability, so your body can absorb chemicals more efficiently.
Smart formulas are tested for how various plant ingredients function synergistically. Clinical studies prove the performance of the product and provide you with evidence-based marketing assistance.


Flexible OEM Services
Complete bespoke production for final product brands. Our team manages formulation development and flexible packaging options for small batches and complete branding assistance including logo and label design whether you need Sialic Acid Powder, capsules, pills or gummies.
Our certificates may be used for your private label goods without the need to spend in duplicate infrastructure.
Quality Assurance You Can Trust
Six-Step Testing Protocol
Production batches are thoroughly tested before shipment. Selection of top raw materials from our regulated planting sites.
Heavy metal and pesticide screening meets EU criteria which are tougher than many regional requirements Microbial safety testing guarantees product safety for delicate applications such as newborn nourishment.
The potency parameters are confirmed by HPLC and UPLC testing of the active ingredient. Supplier audits and third party verification to guarantee quality independently.
International Certifications
Since 2012, we have been working with certifying agencies like as SGS, KOSHER, HALAL, HACCP, cGMP and ISO 22000. These certificates show our dedication to national and regional standards across your worldwide distribution network.
We maintain these certifications via frequent audits of our facilities and goods.

Frequently Asked Questions
Q:What's the difference between fermented and extracted sialic acid?
A:Fermented sialic acid offers consistent purity, year-round availability, and vegan-friendly credentials. Unlike bird's nest extraction, microbial fermentation eliminates seasonal supply variations and provides more predictable pricing for your procurement planning.
Q:Can this ingredient withstand high-temperature processing?
A:Yes, our product maintains stability through pasteurization temperatures. This thermal resilience makes it suitable for spray-drying, hot-fill processes, and other manufacturing methods requiring heat exposure.
Q:How do you ensure batch-to-batch consistency?
A:We control the entire production chain from plant cultivation through final packaging. Automated fermentation systems, real-time monitoring, and standardized testing protocols minimize variation. Each Certificate of Analysis documents specific parameters for your quality records.
Q:What documentation do you provide for regulatory compliance?
A:You receive Certificates of Analysis, allergen statements, GMO status declarations, and certification documents for HALAL, KOSHER, ISO 22000, and other standards. Our regulatory affairs team can provide additional documentation supporting your specific market requirements.
Q:What's your typical lead time for bulk orders?
A:Standard orders ship within 2-3 weeks after payment confirmation. For first-time customers, we recommend ordering samples to verify compatibility with your formulation before placing large volume orders. Our 1 kg MOQ makes initial testing accessible.
Q:Do you offer technical support for formulation development?
A:Our R&D team provides consultation on optimal usage levels, compatibility with other ingredients, and stability testing recommendations. We can suggest formulation approaches based on your target application and desired shelf life.
Packaging & Storage
We provide multiple packaging options suited to your operation scale:
- 1 kg aluminum foil bags for R&D and small batch production
- 5 kg drums for medium-volume manufacturing
- 25 kg fiber drums for large-scale operations
- Custom packaging available for OEM partners
Store in cool, dry conditions away from direct light. Sealed containers maintain product quality throughout the 24-month shelf life. Avoid exposure to moisture and extreme temperatures.
Partner with Bolin Biotechnology Today
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